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Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. Any process that modulates the activity of an enzyme. Any process that stops, prevents or reduces the frequency, rate or extent of guanylate cyclase activity. Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity. Any process that stops or reduces the activity of an enzyme. Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of lyase activity
Acc: GO:0051350
Aspect: Biological Process
Desc: Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
Synonyms:
  • downregulation of lyase activity
  • inhibition of lyase activity
  • down-regulation of lyase activity
  • down regulation of lyase activity
  • lyase inhibitor
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 94 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051350 - negative regulation of lyase activity (interactive image map)

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