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Any process that stops, prevents or reduces the frequency, rate or extent of seed germination. Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell proliferation. Any process that stops, prevents or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response. Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. Any process that stops, prevents, or reduces the rate of production of a cytokine. Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation. Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or group of cells. Any biological process, occurring at the level of a multicellular organism, pertinent to its function. Any process that stops, prevents or reduces the frequency, rate or extent of coagulation. Any process that stops, prevents or reduces the frequency, rate or extent of growth of an organism to reach its usual body size. Any process that stops, prevents or reduces the frequency, rate or extent of vasoconstriction. Any process that decreases the rate, frequency, or extent of the process whereby a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. Any process that stops, prevents, or decreases the frequency, rate, or extent of natriuresis, the process of renal sodium excretion. Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process by which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. Any process that stops, prevents or reduces the frequency, rate or extent of vasodilation. Any process that stops, prevents or reduces the frequency, rate or extent of chitin-based cuticular tanning. Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process by which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. Any process that stops, prevents or reduces the frequency, rate or extent of heart contraction. Any process that stops, prevents or reduces the frequency, rate or extent of a neurophysiological process. Any process that decreases the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death. Any process that stops, prevents or reduces frequency, rate or extent of chemical reactions and pathways in multicellular organisms that occur at the tissue, organ, or organismal level. Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. Any process that stops, prevents or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary. Any process that stops, prevents or reduces the frequency, rate or extent of spore-bearing organ development, a process by which hyphae grow into special aggregates called fruiting bodies that produce new spores. Any process that stops, prevents or reduces the frequency, rate or extent of biomineral formation, the formation of hard tissues that consist mainly of inorganic compounds. Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin. Any process that stops, prevents or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. Any process that stops, prevents or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule. Any process that stops or decreases the rate or extent of hepatocyte differentiation. Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. Any process that stops, prevents or reduces the frequency, rate or extent of hair follicle development. Any process that stops, prevents or reduces the frequency, rate or extent of muscle contraction. Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. Any process that stops, prevents or reduces the frequency, rate, or extent of tissue remodeling. Any process that stops, prevents or reduces the frequency, rate or extent of embryo sac egg cell differentiation. Any process that stops, prevents, or reduces the rate or extent of heat generation. Any process that reduces the rate of diuresis. Diuresis is the process of renal water excretion. Any process that stops, prevents, or reduces the rate or extent of heat dissipation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of multicellular organismal process
Acc: GO:0051241
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
Synonyms:
  • down-regulation of multicellular organismal process
  • downregulation of multicellular organismal process
  • down regulation of multicellular organismal process
  • inhibition of multicellular organismal process
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 508 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051241 - negative regulation of multicellular organismal process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle