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The process whereby a relatively unspecialized cell acquires specialized features of a muscle cell. Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features. Any process that stops, prevents or reduces the frequency, rate or extent of striated muscle cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation. The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. Any process that stops, prevents or reduces the frequency, rate or extent of muscle cell differentiation. Any process that modulates the frequency, rate or extent of muscle cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of muscle cell differentiation
Acc: GO:0051148
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of muscle cell differentiation.
Synonyms:
  • inhibition of muscle cell differentiation
  • down regulation of muscle cell differentiation
  • downregulation of muscle cell differentiation
  • down-regulation of muscle cell differentiation
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 28 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051148 - negative regulation of muscle cell differentiation (interactive image map)
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