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Any cellular process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of DNA ligation
Acc: GO:0051107
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.
Synonyms:
  • inhibition of DNA ligation
  • down regulation of DNA ligation
  • downregulation of DNA ligation
  • down-regulation of DNA ligation
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051107 - negative regulation of DNA ligation (interactive image map)
YRC Informatics Platform - Version 3.0
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