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Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a substance from a cell or group of cells. Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of glutamate. Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a neurotransmitter. The controlled release of a substance by a cell, a group of cells, or a tissue. Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or group of cells. Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of serotonin. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a hormone from a cell or group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of exocytosis. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a catecholamine. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell or group of cells. Any process that stops, prevents, or decreases the frequency, rate, or extent of natriuresis, the process of renal sodium excretion. Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells. The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore. Any process that reduces the rate of diuresis. Diuresis is the process of renal water excretion. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of secretion
Acc: GO:0051048
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a substance from a cell or group of cells.
Synonyms:
  • inhibition of secretion
  • down regulation of secretion
  • down-regulation of secretion
  • downregulation of secretion
Proteins in PDR annotated with:
   This term: 23 [Search]
   Term or descendants: 170 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051048 - negative regulation of secretion (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle