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Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell. Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. Any process that stops, prevents or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell. Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. The signaling process whereby T cell signal transduction is brought to an end rather than being reversibly modulated. A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell. Any process that stops, prevents or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of T cell receptor signaling pathway
Acc: GO:0050860
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
Synonyms:
  • downregulation of T cell receptor signaling pathway
  • negative regulation of T cell receptor signalling pathway
  • negative regulation of T-lymphocyte receptor signaling pathway
  • negative regulation of T-cell receptor signaling pathway
  • inhibition of T cell receptor signaling pathway
  • negative regulation of T lymphocyte receptor signaling pathway
  • negative regulation of TCR signaling pathway
  • negative regulation of T lymphocyte receptor signalling pathway
  • down-regulation of T cell receptor signaling pathway
  • negative regulation of T-lymphocyte receptor signalling pathway
  • down regulation of T cell receptor signaling pathway
Proteins in PDR annotated with:
   This term: 17 [Search]
   Term or descendants: 17 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050860 - negative regulation of T cell receptor signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle