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Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule. Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP. Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule. Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: lactosylceramide 4-alpha-galactosyltransferase activity
Acc: GO:0050512
Aspect: Molecular Function
Desc: Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP.
Synonyms:
  • UDP-galactose:lactosylceramide 4II-alpha-D-galactosyltransferase activity
  • globotriaosylceramide/CD77 synthase activity
  • lactosylceramide 4-a-galactosyltransferase activity
  • histo-blood group Pk UDP-galactose
  • galbeta1-4Glcbeta1-Cer alpha1,4-galactosyltransferase activity
  • Gal-beta-1-4Glc-beta-1-Cer alpha-1,4-galactosyltransferase activity
  • histo-blood group P(k) UDP-galactose activity
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050512 - lactosylceramide 4-alpha-galactosyltransferase activity (interactive image map)
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