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Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor). Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule. Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)](n) + 2n UDP.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: hyaluronan synthase activity
Acc: GO:0050501
Aspect: Molecular Function
Desc: Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)](n) + 2n UDP.
Synonyms:
  • HAS activity
  • spHAS
  • seHAS
  • alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050501 - hyaluronan synthase activity (interactive image map)

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