YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule. Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae, either dihydrosphingosine (DHS) or phytosphingosine (PHS) can react with C26-fattyacyl-CoA to produce ceramide-I or ceramide-II (also called phytoceramide) respectively. In mammals, DHS is usually acylated with a C18 fatty acid group. Catalysis of the generalized reaction: acyl-carrier + reactant = acyl-reactant + carrier.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: sphingosine N-acyltransferase activity
Acc: GO:0050291
Aspect: Molecular Function
Desc: Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae, either dihydrosphingosine (DHS) or phytosphingosine (PHS) can react with C26-fattyacyl-CoA to produce ceramide-I or ceramide-II (also called phytoceramide) respectively. In mammals, DHS is usually acylated with a C18 fatty acid group.
Synonyms:
  • dihydroceramide synthase activity
  • sphingosine acyltransferase activity
  • ceramide synthase activity
  • ceramide synthetase activity
  • acyl-CoA:sphingosine N-acyltransferase activity
Proteins in PDR annotated with:
   This term: 13 [Search]
   Term or descendants: 13 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050291 - sphingosine N-acyltransferase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle