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The process whereby a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. The process whereby the developmental fate of a cell becomes restricted such that it will develop into a stem cell. The process whereby a cell becomes capable of differentiating autonomously into a satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. The process whereby a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: stem cell fate specification
Acc: GO:0048866
Aspect: Biological Process
Desc: The process whereby a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048866 - stem cell fate specification (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle