YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The process whereby a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. The process whereby the developmental fate of a cell becomes restricted such that it will develop into a satellite cell. The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. The process whereby the developmental fate of a cell becomes restricted such that it will develop into a stem cell. The process whereby a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. The process whereby a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: stem cell fate commitment
Acc: GO:0048865
Aspect: Biological Process
Desc: The process whereby the developmental fate of a cell becomes restricted such that it will develop into a stem cell.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048865 - stem cell fate commitment (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle