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The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus. Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes. Any process that modulates the frequency, rate or extent of isotype switching. The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. Any process that activates or increases the frequency, rate or extent of B cell activation. Any process that activates or increases the frequency, rate or extent of isotype switching. Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes. Any process that activates or increases the frequency, rate or extent of DNA recombination.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: positive regulation of isotype switching to IgE isotypes
Acc: GO:0048295
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes.
Synonyms:
  • up-regulation of isotype switching to IgE isotypes
  • positive regulation of class switch recombination to IgE isotypes
  • stimulation of isotype switching to IgE isotypes
  • activation of isotype switching to IgE isotypes
  • up regulation of isotype switching to IgE isotypes
  • positive regulation of isotype switch recombination to IgE isotypes
  • positive regulation of class switching to IgE isotypes
  • upregulation of isotype switching to IgE isotypes
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048295 - positive regulation of isotype switching to IgE isotypes (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle