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Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. An organelle lumen that is part of an intracellular organelle. An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane. The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). The volume enclosed by the membranes of the smooth endoplasmic reticulum. The volume enclosed by the membranes of the endoplasmic reticulum. The smooth endoplasmic reticulum (ER) has with no ribosomes attached to it. The smooth is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: smooth endoplasmic reticulum lumen
Acc: GO:0048238
Aspect: Cellular Component
Desc: The volume enclosed by the membranes of the smooth endoplasmic reticulum.
Synonyms:
  • smooth ER lumen
  • SER lumen
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048238 - smooth endoplasmic reticulum lumen (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle