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Catalysis of the elimination of H2S or substituted H2S. Catalysis of the reaction: L-homocysteine + H2O = sulfide + NH3 + 2-oxobutanoate. Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: homocysteine desulfhydrase activity
Acc: GO:0047982
Aspect: Molecular Function
Desc: Catalysis of the reaction: L-homocysteine + H2O = sulfide + NH3 + 2-oxobutanoate.
Synonyms:
  • homocysteine desulfurase activity
  • L-homocysteine hydrogen-sulfide-lyase (deaminating)
  • L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming)
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047982 - homocysteine desulfhydrase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle