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Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+. Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: estradiol 17-alpha-dehydrogenase activity
Acc: GO:0047881
Aspect: Molecular Function
Desc: Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+.
Synonyms:
  • 17alpha-hydroxy steroid oxidoreductase activity
  • 17alpha-hydroxysteroid oxidoreductase activity
  • 17alpha-hydroxysteroid:NAD(P)+ 17-oxidoreductase activity
  • estradiol 17a-dehydrogenase activity
  • 17alpha-estradiol dehydrogenase activity
  • 17alpha-hydroxy steroid dehydrogenase activity
  • estradiol 17alpha-dehydrogenase activity
  • estradiol 17alpha-oxidoreductase activity
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047881 - estradiol 17-alpha-dehydrogenase activity (interactive image map)
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