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Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone. Catalysis of the reaction: a hydroxynitrile = cyanide + an aldehyde or ketone. Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate. Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: hydroxynitrilase activity
Acc: GO:0047606
Aspect: Molecular Function
Desc: Catalysis of the reaction: a hydroxynitrile = cyanide + an aldehyde or ketone.
Synonyms:
  • 2-hydroxyisobutyronitrile acetone-lyase activity
  • alpha-hydroxynitrile lyase activity
  • acetone-cyanohydrin acetone-lyase activity
  • acetone-cyanohydrin lyase activity
  • oxynitrilase activity
  • 2-hydroxyisobutyronitrile acetone-lyase (cyanide-forming)
  • GO:0046991
  • acetone-cyanhydrin lyase activity
  • hydroxynitrile lyase activity
  • (S)-acetone-cyanohydrin lyase activity
  • acetone-cyanohydrin acetone-lyase (cyanide-forming)
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047606 - hydroxynitrilase activity (interactive image map)
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