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Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + L-lysine + ATP = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ADP. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity
Acc: GO:0047482
Aspect: Molecular Function
Desc: Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + L-lysine + ATP = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ADP.
Synonyms:
  • UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase activity
  • UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase activity
  • UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming)
  • MurE synthetase activity
  • uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase activity
  • L-lysine-adding enzyme activity
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047482 - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity (interactive image map)
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