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Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor). Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP. Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule. Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: globoside alpha-N-acetylgalactosaminyltransferase activity
Acc: GO:0047277
Aspect: Molecular Function
Desc: Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.
Synonyms:
  • uridine diphosphoacetylgalactosamine-globoside alpha-acetylgalactosaminyltransferase activity
  • Forssman synthase activity
  • globoside acetylgalactosaminyltransferase activity
  • UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide alpha-N-acetyl-D-galactosaminyltransferase activity
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047277 - globoside alpha-N-acetylgalactosaminyltransferase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle