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Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: testosterone 17-beta-dehydrogenase (NADP+) activity
Acc: GO:0047045
Aspect: Molecular Function
Desc: Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione.
Synonyms:
  • testosterone 17beta-dehydrogenase (NADP+)
  • 17-ketoreductase activity
  • 17beta-hydroxysteroid:NADP+ 17-oxidoreductase activity
  • NADP-dependent testosterone-17beta-oxidoreductase activity
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047045 - testosterone 17-beta-dehydrogenase (NADP+) activity (interactive image map)
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