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Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 3-alpha(or 20-beta)-hydroxysteroid dehydrogenase activity
Acc: GO:0047044
Aspect: Molecular Function
Desc: Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+.
Synonyms:
  • NADH-20beta-hydroxysteroid dehydrogenase activity
  • (R)-20-hydroxysteroid dehydrogenase activity
  • delta4-3-ketosteroid hydrogenase activity
  • 20beta-hydroxysteroid dehydrogenase activity
  • dehydrogenase, 20beta-hydroxy steroid
  • 3alpha(or 20beta)-hydroxysteroid dehydrogenase activity
  • 3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase activity
  • 20beta-HSD
  • 3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase activity
  • cortisone reductase activity
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047044 - 3-alpha(or 20-beta)-hydroxysteroid dehydrogenase activity (interactive image map)
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Created and Maintained by: Michael Riffle