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Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. Catalysis of the reaction: NADP+ + 5-alpha-androstan-3-beta,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADPH + H+. Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity
Acc: GO:0047024
Aspect: Molecular Function
Desc: Catalysis of the reaction: NADP+ + 5-alpha-androstan-3-beta,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADPH + H+.
Synonyms:
  • 3beta,20alpha-hydroxysteroid oxidoreductase activity
  • 3-beta-HSD activity
  • 3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity
  • dehydrogenase, 3beta,20alpha-hydroxy steroid
  • 3beta(or 20alpha)-hydroxysteroid dehydrogenase activity
  • progesterone reductase activity
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047024 - 3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity (interactive image map)
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Created and Maintained by: Michael Riffle