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Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity
Acc: GO:0047015
Aspect: Molecular Function
Desc: Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.
Synonyms:
  • (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase activity
  • 2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase activity
  • 2-methyl-3-hydroxy-butyryl CoA dehydrogenase activity
  • 2-methyl-3-hydroxybutyryl-CoA dehydrogenase activity
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047015 - 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle