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Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. Catalysis of the reaction: NADP+ + pregnan-21-ol = NADPH + H+ + pregnan-21-al. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: 21-hydroxysteroid dehydrogenase (NADP+) activity
Acc: GO:0047008
Aspect: Molecular Function
Desc: Catalysis of the reaction: NADP+ + pregnan-21-ol = NADPH + H+ + pregnan-21-al.
Synonyms:
  • 21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate) activity
  • 21-hydroxy steroid dehydrogenase activity
  • NADP-21-hydroxysteroid dehydrogenase activity
  • 21-hydroxysteroid:NADP+ 21-oxidoreductase activity
  • 21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047008 - 21-hydroxysteroid dehydrogenase (NADP+) activity (interactive image map)

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