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The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA. The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism. The chemical reactions and pathways resulting in the breakdown of small molecules, any monomeric molecule of small relative molecular mass. The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. The chemical reactions and pathways involving small molecules, any monomeric molecule of small relative molecular mass. The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. The chemical reactions and pathways by which individual cells transform chemical substances.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: ketone body catabolic process
Acc: GO:0046952
Aspect: Biological Process
Desc: The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.
Synonyms:
  • ketone body catabolism
  • ketone body degradation
  • ketone body breakdown
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0046952 - ketone body catabolic process (interactive image map)
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