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The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane. A proton-transporting two-sector ATPase complex found in the lysosomal membrane, where it acts as a proton pump to mediate acidification of the lysosomal lumen. The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane. Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring. A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: lysosomal proton-transporting V-type ATPase, V0 domain
Acc: GO:0046610
Aspect: Cellular Component
Desc: The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.
Synonyms:
  • lysosomal hydrogen ion-transporting ATPase V0 domain
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0046610 - lysosomal proton-transporting V-type ATPase, V0 domain (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle