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Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage. Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: polynucleotide 3'-phosphatase activity
Acc: GO:0046403
Aspect: Molecular Function
Desc: Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage.
Synonyms:
  • polynucleotide 3'-phosphohydrolase activity
  • 5'-polynucleotidekinase 3'-phosphatase activity
  • DNA 3'-phosphatase activity
  • deoxyribonucleate 3'-phosphatase activity
  • 2'(3')-polynucleotidase activity
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0046403 - polynucleotide 3'-phosphatase activity (interactive image map)
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