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Any process that modulates the frequency, rate or extent of complement activation. Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage. Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway. Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes. Any process that activates or increases the frequency, rate or extent of complement activation. Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin. Any process that modulates the frequency, rate or extent of the classical pathway of complement activation. Any process that activates or increases the frequency, rate, or extent of an immune effector process. An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus. Any process that activates or increases the frequency, rate, or extent of a humoral immune response.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: positive regulation of complement activation, classical pathway
Acc: GO:0045960
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway.
Synonyms:
  • up regulation of complement activation, classical pathway
  • stimulation of complement activation, classical pathway
  • activation of complement activation, classical pathway
  • up-regulation of complement activation, classical pathway
  • upregulation of complement activation, classical pathway
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045960 - positive regulation of complement activation, classical pathway (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle