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Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway. Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity. Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Any process that stops, prevents or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. Any process that stops, prevents or reduces the frequency, rate or extent of systemic acquired resistance. Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. Any process that stops, prevents or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. Any process that stops, prevents or reduces the frequency, rate or extent of a defense response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Any process that stops, prevents or reduces the frequency, rate or extent of the hypersensitive response in a plant. Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. Any process that modulates the frequency, rate or extent of a defense response. Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. Any process that stops, prevents or reduces the frequency, rate or extent of complement activation by the alternative pathway. Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection. Any process that stops, prevents or reduces the frequency, rate or extent of the innate immune response.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of innate immune response
Acc: GO:0045824
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the innate immune response.
Synonyms:
  • inhibition of innate immune response
  • down regulation of innate immune response
  • down-regulation of innate immune response
  • downregulation of innate immune response
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 32 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045824 - negative regulation of innate immune response (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle