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Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. Any process that modulates the frequency, rate or extent of the activity of the Wnt receptor mediated signal transduction pathway. Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity. Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC). Any process that stops, prevents or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC). The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state. The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of Wnt receptor signaling pathway, calcium modulating pathway
Acc: GO:0045812
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
Synonyms:
  • down regulation of frizzled-2 signaling pathway
  • negative regulation of frizzled-2 signalling pathway
  • downregulation of frizzled-2 signaling pathway
  • down-regulation of frizzled-2 signaling pathway
  • inhibition of frizzled-2 signaling pathway
  • negative regulation of frizzled-2 signaling pathway
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045812 - negative regulation of Wnt receptor signaling pathway, calcium modulating pathway (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle