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The process whereby a relatively unspecialized thymocyte acquires specialized features of a T-helper cell. The process whereby a relatively unspecialized T cell acquires the specialized features of a Th1 cell. Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha beta T cell differentiation. Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation. Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response. Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation. Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation. An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin. Any process that modulates the frequency, rate or extent of T-helper cell differentiation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: positive regulation of T-helper 1 cell differentiation
Acc: GO:0045627
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.
Synonyms:
  • up regulation of T-helper 1 cell differentiation
  • up-regulation of T-helper 1 cell differentiation
  • stimulation of T-helper 1 cell differentiation
  • activation of T-helper 1 cell differentiation
  • upregulation of T-helper 1 cell differentiation
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045627 - positive regulation of T-helper 1 cell differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle