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Any process that modulates the frequency, rate, or extent of CD4-positive, alpha beta T cell differentiation. The process whereby a relatively unspecialized thymocyte acquires specialized features of a T-helper cell. Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell differentiation. Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. Any process that stops, prevents or reduces the frequency, rate, or extent of CD4-positive, alpha beta T cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell differentiation. The process whereby a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell. The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. Any process that stops, prevents or reduces the frequency, rate or extent of T-helper cell differentiation. Any process that modulates the frequency, rate or extent of T-helper cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of alpha-beta T cell differentiation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of T-helper cell differentiation
Acc: GO:0045623
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of T-helper cell differentiation.
Synonyms:
  • down-regulation of T-helper cell differentiation
  • inhibition of T-helper cell differentiation
  • downregulation of T-helper cell differentiation
  • down regulation of T-helper cell differentiation
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045623 - negative regulation of T-helper cell differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
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