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Any process that stops, prevents or reduces the frequency, rate or extent of B cell differentiation. The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. Any process that modulates the frequency, rate or extent of B cell differentiation. Any process that modulates the frequency, rate or extent of lymphocyte differentiation. Any process that modulates the frequency, rate or extent of B cell activation. Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of B cell activation. The process whereby a precursor cell type acquires the specialized features of a B cell. The process whereby a relatively unspecialized precursor cell acquires specialized features of B cells, T cells, or natural killer cells. Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte activation. Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte differentiation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of B cell differentiation
Acc: GO:0045578
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of B cell differentiation.
Synonyms:
  • inhibition of B cell differentiation
  • negative regulation of B-lymphocyte differentiation
  • negative regulation of B lymphocyte differentiation
  • negative regulation of B-cell differentiation
  • downregulation of B cell differentiation
  • down-regulation of B cell differentiation
  • down regulation of B cell differentiation
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045578 - negative regulation of B cell differentiation (interactive image map)
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