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Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6. Any process that modulates the frequency, rate, or extent of interleukin-6 production. The chemical reactions and pathways resulting in the formation of interleukin-6. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6. The chemical reactions and pathways resulting in the formation of cytokines, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of interleukin-6 biosynthetic process
Acc: GO:0045409
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
Synonyms:
  • downregulation of interleukin-6 biosynthetic process
  • negative regulation of IL-6 biosynthetic process
  • negative regulation of interleukin-6 synthesis
  • negative regulation of IL-6 biosynthesis
  • down-regulation of interleukin-6 biosynthetic process
  • inhibition of interleukin-6 biosynthetic process
  • negative regulation of interleukin-6 biosynthesis
  • down regulation of interleukin-6 biosynthetic process
  • negative regulation of interleukin-6 anabolism
  • negative regulation of interleukin-6 formation
Proteins in PDR annotated with:
   This term: 7 [Search]
   Term or descendants: 7 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045409 - negative regulation of interleukin-6 biosynthetic process (interactive image map)
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