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Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II. Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II. Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of MHC class II biosynthetic process
Acc: GO:0045347
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms:
  • inhibition of MHC class II biosynthetic process
  • negative regulation of major histocompatibility complex class II biosynthetic process
  • down-regulation of MHC class II biosynthetic process
  • downregulation of MHC class II biosynthetic process
  • down regulation of MHC class II biosynthetic process
  • negative regulation of MHC class II synthesis
  • negative regulation of MHC class II anabolism
  • negative regulation of MHC class II biosynthesis
  • negative regulation of major histocompatibility complex class II biosynthesis
  • negative regulation of MHC class II formation
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045347 - negative regulation of MHC class II biosynthetic process (interactive image map)

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