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A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that activates or increases the frequency, rate, or extent of leukocyte activation. Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. Any process that modulates the frequency, rate, or extent of leukocyte activation. The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation. Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand. A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: leukocyte activation
Acc: GO:0045321
Aspect: Biological Process
Desc: A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
Synonyms:
  • immune cell activation
  • leucocyte activation
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 650 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045321 - leukocyte activation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle