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Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes. Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes. Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. An immune response mediated by immunoglobulins, whether cell-bound or in solution. Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response. Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes. Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes. Any process that modulates the frequency, rate, or extent of B cell mediated immunity. A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. Any biological process, occurring at the level of a multicellular organism, pertinent to its function. Any process that stops, prevents or reduces the frequency, rate or extent of isotype switching. The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response. Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that modulates the frequency, rate, or extent of immunoglobulin production. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA. Any process that modulates the frequency, rate or extent of B cell activation. Any process that modulates the frequency, rate or extent of isotype switching. The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. Any process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. Any process that modulates the frequency, rate or extent of lymphocyte activation. The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). Any process that activates or increases the frequency, rate or extent of isotype switching. Any process that modulates the frequency, rate or extent of DNA recombination, a process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: regulation of isotype switching
Acc: GO:0045191
Aspect: Biological Process
Desc: Any process that modulates the frequency, rate or extent of isotype switching.
Synonyms:
  • regulation of isotype switch recombination
  • regulation of class switching
  • regulation of class switch recombination
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 28 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045191 - regulation of isotype switching (interactive image map)
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