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The chemical reactions and pathways involving chemokines, any of a subgroup of cytokines which act primarily on hemopoietic cells in acute and inflammatory processes and other immunoregulatory functions. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation. The chemical reactions and pathways resulting in the formation of chemokines, any of a subgroup of cytokines which act primarily on hemopoietic cells in acute and inflammatory processes and other immunoregulatory functions. The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines. Any process that modulates the frequency, rate, or extent of chemokine production. The chemical reactions and pathways resulting in the formation of cytokines, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of chemokine biosynthetic process
Acc: GO:0045079
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines.
Synonyms:
  • down regulation of chemokine biosynthetic process
  • negative regulation of chemokine biosynthesis
  • downregulation of chemokine biosynthetic process
  • negative regulation of chemokine formation
  • inhibition of chemokine biosynthetic process
  • negative regulation of chemokine anabolism
  • negative regulation of chemokine synthesis
  • down-regulation of chemokine biosynthetic process
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045079 - negative regulation of chemokine biosynthetic process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle