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Any process that stops, prevents, or reduces the rate of mast cell degranulation. Any process that modulates the frequency, rate, or extent of mast cell degranulation. The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell. Any process involved in the carrying out of an immune response by a mast cell. The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors. The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. Any process involved in the carrying out of an immune response by a myeloid leukocyte. The regulated exocytosis of secretory granules by a leukocyte. Any process that activates or increases the frequency, rate or extent of mast cell degranulation. A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand. Any process of the immune system that occurs as part of an immune response. The regulated release of histamine by a mast cell or group of mast cells. The regulated release of serotonin by a mast cell or group of mast cells. A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: mast cell degranulation
Acc: GO:0043303
Aspect: Biological Process
Desc: The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.
Synonyms:
  • mast cell granule exocytosis
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 34 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043303 - mast cell degranulation (interactive image map)

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