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Any process that stops, prevents, or reduces the rate of neutrophil degranulation. Any process that stops, prevents, or reduces the rate of mast cell degranulation. Any process that stops, prevents, or reduces the rate of natural killer cell degranulation. Any process that stops, prevents, or reduces the rate of eosinophil degranulation. Any process that stops, prevents, or reduces the rate of leukocyte degranulation. Any process that modulates the frequency, rate, or extent of leukocyte degranulation. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a substance from a cell or group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation. A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells. The regulated exocytosis of secretory granules by a leukocyte. Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. Any process that modulates the frequency, rate, or extent of an immune effector process. Any process that stops, prevents or reduces the frequency, rate or extent of exocytosis. A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand. Any process of the immune system that occurs as part of an immune response. Any process that modulates the frequency, rate or extent of exocytosis.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of leukocyte degranulation
Acc: GO:0043301
Aspect: Biological Process
Desc: Any process that stops, prevents, or reduces the rate of leukocyte degranulation.
Synonyms:
  • negative regulation of immune cell degranulation
  • down regulation of leukocyte degranulation
  • down-regulation of leukocyte degranulation
  • downregulation of leukocyte degranulation
  • inhibition of leukocyte degranulation
  • negative regulation of leucocyte degranulation
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043301 - negative regulation of leukocyte degranulation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle