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The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell. The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell. Any process that activates or increases the frequency, rate or extent of leukocyte degranulation. The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell. Any process that stops, prevents, or reduces the rate of leukocyte degranulation. Any process that modulates the frequency, rate, or extent of leukocyte degranulation. The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil. A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells. The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil. The regulated exocytosis of secretory granules by a leukocyte. A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand. The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil. Any process of the immune system that occurs as part of an immune response. Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: leukocyte degranulation
Acc: GO:0043299
Aspect: Biological Process
Desc: The regulated exocytosis of secretory granules by a leukocyte.
Synonyms:
  • immune cell degranulation
  • leukocyte granule exocytosis
  • immune cell granule exocytosis
  • leucocyte degranulation
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 45 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043299 - leukocyte degranulation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle