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A part of an axon, a cell projection of a neuron. Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman clefts occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier. The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. The portion of the myelin sheath in which layers of cell membrane are tightly juxtaposed, completely excluding cytoplasm. The juxtaposed cytoplasmic surfaces form the major dense line, while the juxtaposed extracellular surfaces form the interperiod line visible in electron micrographs. Any constituent part of a cell, the basic structural and functional unit of all organisms. Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: Schmidt-Lanterman cleft
Acc: GO:0043220
Aspect: Cellular Component
Desc: Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman clefts occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier.
Synonyms:
  • GO:0044287
  • Schmidtt-Lanterman cleft
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043220 - Schmidt-Lanterman cleft (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle