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A process by which a protein is transported to, or maintained in, a location within the nucleus. The directed movement of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane. The directed movement of substances into the nucleus. The directed movement of proteins into a cell or organelle. The directed movement of NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors, from the cytoplasm into the nucleus. NFAT proteins are dephosphorylated in the cytoplasm by activated calcineurin, which leads to their translocation across the nuclear membrane. The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. Any process that stops, prevents or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. The directed movement of a protein from the cytoplasm to the nucleus. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. Any process that modulates the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. The directed movement of a transcription factor from the cytoplasm to the nucleus.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: transcription factor import into nucleus
Acc: GO:0042991
Aspect: Biological Process
Desc: The directed movement of a transcription factor from the cytoplasm to the nucleus.
Synonyms:
  • transcription factor-nucleus import
  • transcription factor import into cell nucleus
  • transcription factor transport from cytoplasm to nucleus
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 92 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042991 - transcription factor import into nucleus (interactive image map)
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Created and Maintained by: Michael Riffle