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A membrane-bounded vesicle found in the cytoplasm of the cell. Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. A lysosome before it has fused with a vesicle or vacuole.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: azurophil granule
Acc: GO:0042582
Aspect: Cellular Component
Desc: Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
Synonyms:
  • primary granule
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042582 - azurophil granule (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle