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Any process that terminates the activity of the active enzyme MAP kinase. A MAPKKK cascade culminating in the phosphorylation and activation of a MAP kinase that occurs in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response. The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response. A cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Any process that stops, prevents or reduces the frequency, rate or extent of MAP kinase activity. Any process that terminates the activity of the active enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: inactivation of MAPK activity involved in innate immune response
Acc: GO:0035423
Aspect: Biological Process
Desc: Any process that terminates the activity of the active enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0035423 - inactivation of MAPK activity involved in innate immune response (interactive image map)
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