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The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division. The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell. Any process that modulates the frequency, rate or extent of macrophage fusion. Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion. The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. Any process that activates or increases the frequency, rate or extent of macrophage fusion.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: macrophage fusion
Acc: GO:0034238
Aspect: Biological Process
Desc: The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 9 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0034238 - macrophage fusion (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle