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Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters. Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters. Catalysis of the reaction: two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates. Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: ribonuclease T2 activity
Acc: GO:0033897
Aspect: Molecular Function
Desc: Catalysis of the reaction: two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.
Synonyms:
  • RNase II activity
  • ribonuclease U4 activity
  • RNAase CL activity
  • Escherichia coli ribonuclease I' ribonuclease PP2 activity
  • RNase Ms activity
  • nonspecific RNase activity
  • ribonuclease PP3 activity
  • RNase T2 activity
  • base-non-specific ribonuclease activity
  • nonbase-specific RNase activity
  • ribonuclease (non-base specific) activity
  • non-base specific ribonuclease activity
  • ribonuclease N2 activity
  • Escherichia coli ribonuclease II activity
  • ribonuclease II activity
  • RNase (non-base specific) activity
  • ribonucleate nucleotido-2'-transferase (cyclizing) activity
  • acid ribonuclease activity
  • acid RNase activity
  • ribonnuclease (non-base specific) activity
  • ribonuclease M activity
  • ribonucleate 3'-oligonucleotide hydrolase activity
  • RNase M activity
Proteins in PDR annotated with:
   This term: 12 [Search]
   Term or descendants: 12 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0033897 - ribonuclease T2 activity (interactive image map)
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