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Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule. Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: DNA 5'-adenosine monophosphate hydrolase activity
Acc: GO:0033699
Aspect: Molecular Function
Desc: Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.
Synonyms:
  • AMP-removal activity
  • DNA deadenylation
  • DNA adenylate hydrolysis activity
  • DNA 5'-adenylate hydrolase activity
  • DNA de-adenylation
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0033699 - DNA 5'-adenosine monophosphate hydrolase activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle