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Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate. Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate. Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity. Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: MAP kinase phosphatase activity
Acc: GO:0033549
Aspect: Molecular Function
Desc: Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate.
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 48 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0033549 - MAP kinase phosphatase activity (interactive image map)
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