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Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. Any process that stops, prevents, or reduces the rate of production of a cytokine. The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Any process that modulates the frequency, rate, or extent of production of a cytokine. Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production. Any process that modulates the frequency, rate, or extent of interleukin-18 production.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of interleukin-18 production
Acc: GO:0032701
Aspect: Biological Process
Desc: Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production.
Synonyms:
  • inhibition of interleukin-18 production
  • down-regulation of interleukin-18 production
  • down regulation of interleukin-18 production
  • negative regulation of IL-18 production
  • downregulation of interleukin-18 production
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032701 - negative regulation of interleukin-18 production (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle