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A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2. A membrane-bounded vesicle found in the cytoplasm of the cell. A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: insulin-responsive compartment
Acc: GO:0032593
Aspect: Cellular Component
Desc: A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2.
Synonyms:
  • GSC
  • IRC
  • GLUT4 storage compartment
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032593 - insulin-responsive compartment (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle